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Irinotecan Hydrochloride trihydrate

Alias: (+)-7-Ethyl-10-hydroxycamptothecine 10-(1,4'-bipiperidine)-1'-carboxylate, monohydrochloride, trihydrate; Camptosar; Irinotecan HCl trihydrate; (1,4'-Bipiperidine)-1'-carboxylic acid, 4,11-diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano(3',4':6,7)indolizino(1,2-b)quinolin-9-yl ester, monohydrochloride, trihydrate, (S)-; (1,4'-bipiperidine)-1'-carboxylicacid,4,11-diethyl-3,4,12,14-tetrahydro-4-hyd monohydrochloride, trihydrate; roxy-3,14-dioxo-1h-pyrano(3',4',6,7)indolizino(1,2-b)quinolin-9-ylester,mono; trihydrate,(s)-hydrochlorid trihydrate; irinotecan monohydrochloride trihydrate; [1,4'-bipiperidine]-1'-carboxylic acid (s)-4,11-diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1h-pyrano; [3',4',6,7]indolizino[1,2-b]quinolin-9-yl ester, hcl trihydrate; (s)-[1,4'-bipiperidine]-1'-carboxylic acid 4,11-diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1h-pyrano; [3',4':6,7]indolizino[1,2-b]quinolin-9-yl ester hydrochloride trihydrate; irinotecanhydrochloridetrihydrate(cpt-11)

CAS Reg. 136572-09-3;

Molecular formula: C33H38N4O6?HCL?3H2O;

Molecular weight: 677.19;

Appearance: light yellow or yellow clean powder, odorless

Solubility: lightly soluble in water, ethyl alcohol and chloroform; nearly insoluble in acetone

Specific optical rotation: +63.0° to 69.0°

Moisture: 7%-9%;

PH: 3.0-5.0;

6Heavy metal: ≤20PPM;

7Residue on ignition:≤0.1%;

8Purity: ≥98%(by HPLC);

Indication: for tumour, for example, stomach cancer, intestinal cancer, chorionic epithelioma, lymphatic sarcoma


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